# Trends and hotspots in autoimmune hepatitis research: based on bibliometric analysis

**Authors:** Ruisi Li, Yue Xu, XiaoYing Xu, YiHeng Xu, Haitang Huang, Xiaojuan Lv, Chu Liao, Junqiu Ye, Bo Liu, Hengfei Li

PMC · DOI: 10.1186/s41065-025-00477-6 · Hereditas · 2025-07-01

## TL;DR

This paper uses bibliometric analysis to track trends and hotspots in autoimmune hepatitis research from 2003 to 2023, identifying key contributors and future directions.

## Contribution

The study provides a systematic bibliometric overview of AIH research, highlighting growth, key players, and emerging trends.

## Key findings

- AIH research output has grown significantly, peaking in 2023.
- The US, China, and Japan are leading contributors to AIH research.
- Key institutions include the University of London, Mayo Clinic, and King's College Hospital NHS Foundation Trust.

## Abstract

Autoimmune Hepatitis (AIH) is a chronic inflammatory liver disease characterized by a sustained inflammatory response in the liver, usually associated with abnormalities in the immune system.The purpose of this study was to utilize bibliometric analysis to assess the current state of research on AIH and to predict future research areas and emerging trends.

In this study, we used bibliometric analysis to comprehensively analyze the literature on Autoimmune Hepatitis (AIH) published during the past two decades.

Literature from 2003 to 2023 was retrieved from the Web of Science Core Collection, the world's leading citation indexing database. Visualization and analysis were performed using VOSviewer 1.6.18 and CiteSpace 6.2.R3 software.

The study covered 6,390 papers by 28,037 authors from 291 institutions in 110 countries. AIH research output grew significantly, peaking in 2023. The US was the top contributor, followed by China and Japan. Notable institutions included the University of London, Mayo Clinic, and King's College Hospital NHS Foundation Trust. AIH research spans medicine, healthcare, clinical sciences, molecular biology, immunology, etc.

In this paper, we have used bibliometric analysis to systematically review and analyze the research literature on autoimmune hepatitis (AIH) over the past two decades. This comprehensive overview aims to provide scholars dedicated to this field with a clear research lineage and future research directions.

## Linked entities

- **Diseases:** Autoimmune Hepatitis (MONDO:0016264)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), inflammatory liver disease (MESH:D008107), AIH (MESH:D019693)

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12211198/full.md

## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12211198/full.md

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Source: https://tomesphere.com/paper/PMC12211198