# Vertebral Metastasis With Syringomyelia Secondary to Breast Adenocarcinoma: A Case Report and Literature Review

**Authors:** Ahmed Reda Abdelhalim, Hossam Tharwat Ali, Bishoy Adel Kamel Zakher, Yara Ashour

PMC · DOI: 10.1002/ccr3.70580 · Clinical Case Reports · 2025-07-01

## TL;DR

A 34-year-old woman with breast cancer developed syringomyelia and spinal issues after treatment, highlighting the need for neurological monitoring in cancer patients.

## Contribution

This case report adds to the literature on syringomyelia as a rare complication of vertebral metastasis and cancer treatment.

## Key findings

- A patient with breast cancer and vertebral metastasis developed syringomyelia and myelopathy.
- Neurological symptoms following cancer treatment may indicate complications like syringomyelia.
- Further clinical awareness and documentation of such cases are recommended.

## Abstract

Syringomyelia has several possible causes, commonly including Chiari malformation, spinal cord tumors and injuries, and damage caused by lesions around the spinal cord. A 34‐year‐old female was diagnosed with primary breast cancer and vertebral metastasis and was initiated on an extensive regimen of chemotherapy and radiotherapy. A few months later, she developed numbness and weakness in her lower limbs, and she was concluded to have syringomyelia with surrounding atrophic myelopathy along with vertebral metastasis. Patients developing neurological symptoms following radiotherapy or chemotherapy should be thoroughly evaluated, and further cases should be reported in the literature.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989), syringomyelia (MONDO:0017987)

## Full-text entities

- **Diseases:** Vertebral Metastasis (MESH:D009362), weakness (MESH:D018908), neurological symptoms (MESH:D009461), Chiari malformation (MESH:D001139), injuries (MESH:D014947), atrophic myelopathy (MESH:D013118), numbness (MESH:D006987), spinal cord tumors (MESH:D013120), Syringomyelia (MESH:D013595), Breast Adenocarcinoma (MESH:D001943)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12210029/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12210029/full.md

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Source: https://tomesphere.com/paper/PMC12210029