# A Rare Tumor in a Septuagenarian Female 16 Years After Radical Mastectomy for Breast Carcinoma

**Authors:** Mohammadhossein Rahimirad, Sara Daneshvar, Shaghayegh Rahimirad, Monireh Halimi, Akbar Sharifi

PMC · DOI: 10.1002/ccr3.70574 · Clinical Case Reports · 2025-07-01

## TL;DR

A 70-year-old woman developed a rare lung tumor 16 years after breast cancer treatment, marking the first reported case of this kind.

## Contribution

This is the first documented case of multiple pleuropulmonary spindle cell carcinoma following breast cancer.

## Key findings

- A rare case of pleuropulmonary spindle cell carcinoma was identified 16 years after breast cancer treatment.
- The patient had a history of mastectomy and chemotherapy for breast carcinoma.
- This case highlights the potential for long-term development of second primary cancers.

## Abstract

Pleuropulmonary spindle cell carcinoma (SpCC) is a very rare tumor that belongs to a subgroup of sarcomatoid carcinomas of non‐small cell carcinomas of the lung. Breast carcinoma is one of the most common malignancies associated with metachronous second primary cancers. To our knowledge, this is the first report of a rare case of multiple pleuropulmonary SpCC in a 70‐year‐old woman, 16 years after mastectomy and chemotherapy for breast carcinoma.

## Linked entities

- **Diseases:** breast carcinoma (MONDO:0004989)

## Full-text entities

- **Diseases:** Breast Carcinoma (MESH:D001943), Tumor (MESH:D009369), sarcomatoid carcinomas of non-small cell carcinomas of the lung (MESH:D002289), Pleuropulmonary spindle cell carcinoma (MESH:D002277)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12209863/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12209863/full.md

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Source: https://tomesphere.com/paper/PMC12209863