# Editorial: Ferroptosis: intersections, implications, and innovations in programmed cell death

**Authors:** Bilal Cig, Patrice X. Petit, Juan Carlos Mayo

PMC · DOI: 10.3389/fcell.2025.1635046 · 2025-06-17

## Full-text entities

- **Genes:** STING1 (stimulator of interferon response cGAMP interactor 1) [NCBI Gene 533661] {aka STING, TMEM173}, TFRC (transferrin receptor) [NCBI Gene 504698], HMOX1 (heme oxygenase 1) [NCBI Gene 513221] {aka HO-1}, CD44 (CD44 molecule) [NCBI Gene 281057], NFE2L2 (NFE2 like bZIP transcription factor 2) [NCBI Gene 497024] {aka NRF2}, GCH1 (GTP cyclohydrolase 1) [NCBI Gene 286815], Tbeta4 [NCBI Gene 781334], SLC7A11 (solute carrier family 7 member 11) [NCBI Gene 524078], PTGS2 (prostaglandin-endoperoxide synthase 2) [NCBI Gene 282023], CDKN1A (cyclin dependent kinase inhibitor 1A) [NCBI Gene 513497] {aka CIP1, SDI1, WAF1, p21}, SOX13 (SRY-box transcription factor 13) [NCBI Gene 788459], GPX4 (glutathione peroxidase 4) [NCBI Gene 286809] {aka PHGPx}, NCOA4 (nuclear receptor coactivator 4) [NCBI Gene 525329], SIRT1 (sirtuin 1) [NCBI Gene 613629], TP73 (tumor protein p73) [NCBI Gene 515105], CA9 (carbonic anhydrase 9) [NCBI Gene 511923]
- **Diseases:** osteoarthritis (MESH:D010003), neurodegeneration (MESH:D019636), inflammation (MESH:D007249), reperfusion injury (MESH:D015427), metabolic disorders (MESH:D008659), AKI (MESH:D058186), necrosis (MESH:D009336), IDD (MESH:D055959), NAFLD (MESH:D065626), renal ischemia (MESH:D007511), THCA (MESH:D013964), diabetes (MESH:D003920), cancer (MESH:D009369), renal damage (MESH:D007674)
- **Chemicals:** Iron (MESH:D007501), cisplatin (MESH:D002945), NAD+ (MESH:D009243), ROS (MESH:D017382), GSH (MESH:D005978), BH4 (MESH:C003402), PUFAs (MESH:D005231), baicalein (MESH:C006680), CoQ10 (MESH:C024989), lipid (MESH:D008055), Chinese medicine (-), ginkgolide B (MESH:C045856), alpha-tocopherol (MESH:D024502)
- **Species:** Bos taurus (bovine, species) [taxon 9913]

---
Source: https://tomesphere.com/paper/PMC12209272