# Intravascular Myopericytoma of the Foot: A Diagnostic Challenge

**Authors:** Taro Fujimaki, Tomonori Kawasaki, Masanori Wako, Kojiro Onohara, Jiro Ichikawa

PMC · DOI: 10.7759/cureus.85110 · 2025-05-30

## TL;DR

This paper presents a rare case of a foot tumor that was difficult to diagnose and highlights the importance of histopathology for accurate identification.

## Contribution

The paper reports a rare intravascular myopericytoma case in the foot and emphasizes the need for histopathological analysis in diagnosis.

## Key findings

- MRI findings were inconclusive, but histopathology confirmed the tumor as myopericytoma.
- No recurrence was observed after three years following marginal excision.
- Histopathological analysis is crucial for distinguishing myopericytoma from similar tumors.

## Abstract

Myopericytoma is a rare pericytic tumor, typically occurring in the skin and subcutaneous tissue, though cases in internal organs and bones have been reported. Clinically, it presents as a painless, slow-growing mass, making differential diagnosis challenging. Imaging alone is often insufficient due to overlapping characteristics with angioleiomyoma, glomus tumors, and solitary fibrous tumors (SFT). Histopathological examination is essential for accurate diagnosis. Here, we report a rare case of intravascular myopericytoma of the foot. MRI findings suggested multiple differential diagnoses, but histopathology confirmed the tumor. Immunohistochemistry supported the diagnosis. Marginal excision was performed, and no recurrence was observed after three years. Given the overlapping imaging characteristics of pericytic tumors, histopathological analysis is crucial for distinguishing myopericytoma from similar entities and ensuring proper treatment and management. This case highlights the importance of comprehensive evaluation when diagnosing pericytic tumors in distal extremities.

## Full-text entities

- **Diseases:** glomus tumors (MESH:D005918), SFT (MESH:D054364), angioleiomyoma (MESH:D018229), Myopericytoma (MESH:D000077777), pericytic tumor (MESH:D009369)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12208813/full.md

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Source: https://tomesphere.com/paper/PMC12208813