# Reddish-Brown Dermal Papules and Plaques in a Patient With Kidney Stones

**Authors:** Abhishek P Mullapudi, Lydia A Luu, Mary Noland

PMC · DOI: 10.7759/cureus.85076 · 2025-05-30

## TL;DR

A young man with kidney stones and skin lesions was diagnosed with sarcoidosis, showing the need for a full evaluation of this systemic disease.

## Contribution

This case report emphasizes cutaneous signs as early indicators of systemic sarcoidosis.

## Key findings

- A patient presented with kidney stones and skin lesions, later diagnosed with sarcoidosis.
- Biopsy confirmed cutaneous sarcoidosis with pulmonary and renal involvement.
- Treatment with hydroxychloroquine and prednisone improved skin lesions.

## Abstract

Sarcoidosis is a systemic inflammatory disease affecting multiple organs including the skin, lungs, and kidneys. This case report describes a man in his late 20s presenting with recurrent kidney stones and a one-year history of progressive, asymptomatic lesions on his scalp, forehead, trunk, and feet, with dyspnea on exertion. Biopsy confirmed cutaneous sarcoidosis, and further evaluation revealed pulmonary and renal involvement. He was treated with hydroxychloroquine and prednisone, leading to improvement in skin lesions. This case highlights the importance of recognizing cutaneous manifestations as potential indicators of systemic sarcoidosis, and the need for a comprehensive, multidisciplinary approach to diagnosis and management.

## Linked entities

- **Chemicals:** hydroxychloroquine (PubChem CID 3652), prednisone (PubChem CID 5865)
- **Diseases:** sarcoidosis (MONDO:0008399)

## Full-text entities

- **Diseases:** inflammatory disease (MESH:D007249), cutaneous (MESH:D018366), Sarcoidosis (MESH:D012507), pulmonary and renal involvement (MESH:C565423), skin lesions (MESH:D012871), dyspnea (MESH:D004417), Kidney Stones (MESH:D007669)
- **Chemicals:** hydroxychloroquine (MESH:D006886), prednisone (MESH:D011241)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12208512/full.md

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Source: https://tomesphere.com/paper/PMC12208512