# Molecular docking analysis of bioactive molecules from herbs with snake venom phospholipase A2

## TL;DR

This paper identifies plant-derived compounds that strongly inhibit snake venom phospholipase A2, suggesting potential herbal treatments.

## Contribution

The study evaluates and identifies novel bioactive phytoconstituents as potent inhibitors of snake venom PLA2.

## Key findings

- Gymnemic acid, Aristolochic acid, Lupeol, and Tocopherol show strong inhibitory potential against PLA2.
- These compounds exhibit strong binding and molecular interactions with snake venom phospholipase A2.

## Abstract

Snake venom, particularly phospholipase A2 (PLA2), exerts profound pathological effects, necessitating the development of potent
therapeutic interventions. Therefore, it is of interest to the inhibitory potential of bioactive phytoconstituents from select medicinal
herbs with PLA2. Analysis showed that Gymnemic acid, Aristolochic acid, Lupeol and Tocopherol are the best PLA2 inhibitors with strong
binding and molecular interactions for further consideration.