# Clinical presentation and microbial culture among osteomyelitis patients

**Authors:** Babita Kumari, Rashmi Prabha, Vijay Kumar

PMC · DOI: 10.6026/973206300210309 · 2025-03-31

## TL;DR

This study examines the symptoms and microbial causes of osteomyelitis in 200 patients to improve diagnosis and treatment.

## Contribution

The study provides insights into common clinical features and microbial cultures in osteomyelitis patients.

## Key findings

- Tibia was the most commonly affected bone, often due to trauma.
- Staphylococcus aureus, Escherichia coli, and Klebsiella spp. were frequently isolated from microbial cultures.
- Common symptoms included fever, pain, swelling, and inability to bear weight.

## Abstract

Clinical presentation and microbial culture among osteomyelitis patients is required for proper diagnosis and management. Therefore,
it is of interest to evaluate the clinical presentation and microbial culture among osteomyelitis patients. Hence, 200 patients with
osteomyelitis having clinical symptoms and radiological findings were qualified for participation. Specimens such as synovial fluid,
bone sequestrum, pus swabs and pus were collected aseptically and examined for microbial growth. Clinical assessment of osteomyelitis
patient showed that most commonly affected bone was tibia with trauma. Inability to bear weight was commonly observed with symptoms like
fever, pain, or tenderness and swelling where infection is the predisposing factor for osteomyelitis. Further, different microorganisms
like Staphylococcus aureus, Escherichia coli, Klebsiella spp, etc.
were found in microbial culture.

## Linked entities

- **Diseases:** osteomyelitis (MONDO:0005246)

## Full-text entities

- **Diseases:** pain (MESH:D010146), swelling (MESH:D004487), tenderness (MESH:D063806), trauma (MESH:D014947), osteomyelitis (MESH:D010019), fever (MESH:D005334), infection (MESH:D007239), bone sequestrum (MESH:D001847)
- **Species:** Homo sapiens (human, species) [taxon 9606], Escherichia coli (E. coli, species) [taxon 562], Staphylococcus aureus (species) [taxon 1280], Klebsiella (genus) [taxon 570]

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Source: https://tomesphere.com/paper/PMC12208263