# Echoes of healing: evaluating therapeutic ultrasound in oral submucous fibrosis - An experimental study

**Authors:** Aparna Raj, Annette M. Bhambal, Palak Choudhary, Rashmi D. Sathe, Karishma Upadhyay, Parnavi Mishra

PMC · DOI: 10.6026/973206300210467 · 2025-03-31

## TL;DR

This study finds that combining ultrasound therapy with jaw exercises is most effective for treating oral submucous fibrosis.

## Contribution

The novel contribution is identifying combination therapy as superior to individual treatments for this condition.

## Key findings

- Combination therapy showed the most significant improvement in symptoms compared to individual treatments.
- Ultrasound combined with jaw-opening exercises was found to be the most effective treatment modality.
- Statistical analysis confirmed significant improvements in mouth opening and cheek flexibility with combination therapy.

## Abstract

The effectiveness of therapeutic ultrasound in managing Grade II and III oral submucous fibrosis is of interest. Sixty patients were
divided into three groups: ultrasound therapy alone, active physiotherapy alone and a combination of both. Patients were assessed for
burning sensation, maximum mouth opening, and cheek flexibility. Statistical analysis (p<0.05) confirmed that combination therapy
provided the most significant improvement. The findings suggest that ultrasound therapy combined with active physiotherapy, specifically
jaw-opening exercises, is the most effective treatment modality for oral submucous fibrosis.

## Linked entities

- **Diseases:** oral submucous fibrosis (MONDO:0018166)

## Full-text entities

- **Diseases:** submucous fibrosis (MESH:D009914)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12208255