# An overview on H5N1 virus: Recent outbreaks and challenges

**Authors:** Atul Rukadikar, Shruti Dalpatbhai Kalola, Srushti J. Bhoraniya, Komal Ravi Thaker, Charushila Rukadikar

PMC · DOI: 10.6026/973206300210544 · 2025-03-31

## TL;DR

This paper provides an overview of the H5N1 virus, its recent outbreaks, and the challenges it poses to both birds and mammals.

## Contribution

The paper offers a concise summary of H5N1's recent developments and their implications for disease management.

## Key findings

- H5N1 is a highly infectious virus causing severe respiratory disease in birds and can infect mammals.
- New strains with mutations are increasing the virus's pathogenicity and virulence.
- Infected dairy cows or chickens are likely sources of disease outbreaks, impacting agriculture and the food industry.

## Abstract

Avian influenza - A (H5N1) is a type of virus that causes highly infectious, severe respiratory influenza disease in birds. It also
infects mammals rising concerns about its re-assortment and increased virulence. New strains with mutations have been making the virus
more pathogenic. The more likely source for disease outbreak is from dairy cows or chickens that are infected. This presents a
considerable source of economic detriment for both agricultural producers and the food industry. Hence, a concise overview on H5N1 to
enhance the understanding of its infection for adequate disease combat and management is relevant.

## Full-text entities

- **Diseases:** respiratory influenza disease (MESH:D012140), infection (MESH:D007239)
- **Species:** H5N1 subtype (serotype) [taxon 102793], Bos taurus (bovine, species) [taxon 9913], Gallus gallus (bantam, species) [taxon 9031]

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Source: https://tomesphere.com/paper/PMC12208241