# Risk of cardiovascular events among celiac disease patients: A meta-analysis review

**Authors:** Saad Shams, Vanessa Vidaurre Corrales, Ibrahim Marouf Yasin Al Shyyab, Akshat Banga, Ameer Mustafa Farrukh, Moza Ali Alzaabi, Majd Atef Albeetar, Sem Josue Nsanh Yao, Kavya Remala, Mohamad Emad Aldeen Mahfouz, Navneeth Jayaprakash, Sawai Singh Rathore

PMC · DOI: 10.6026/973206300210375 · 2025-03-31

## TL;DR

This study reviews the link between celiac disease and cardiovascular events, finding no overall increased risk but higher chances of specific conditions like stroke and heart failure.

## Contribution

The study provides a meta-analysis of cardiovascular risks in celiac disease patients, highlighting specific conditions of concern.

## Key findings

- Celiac disease patients had a 9.3% prevalence of cardiovascular events.
- No significant overall cardiovascular risk increase compared to the general population.
- Higher risk of atrial fibrillation, stroke, heart failure, and cardiomyopathy was observed.

## Abstract

A review on the association between celiac disease and cardiovascular events using multiple databases and random effects models is of
interest. The overall prevalence of cardiovascular events in celiac patients was 9.3%. However, there was no significant increase in
overall cardiovascular risk or myocardial infarction compared to the general population. Known data shows that celiac disease was linked
to a higher risk of atrial fibrillation, stroke, congestive heart failure and cardiomyopathy. Thus, there is a need to monitor
cardiovascular health in celiac patients to mitigate potential risks.

## Linked entities

- **Diseases:** celiac disease (MONDO:0005130), myocardial infarction (MONDO:0005068), atrial fibrillation (MONDO:0004981), stroke (MONDO:0005098), congestive heart failure (MONDO:0005009), cardiomyopathy (MONDO:0004994)

## Full-text entities

- **Diseases:** stroke (MESH:D020521), atrial fibrillation (MESH:D001281), myocardial infarction (MESH:D009203), cardiomyopathy (MESH:D009202), congestive heart failure (MESH:D006333), celiac (MESH:D002446)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12208236