# Optimized synthesis of aroyl-S,N-ketene acetals by omission of solubilizing alcohol cosolvents

## TL;DR

A new, efficient method for making aroyl-S,N-ketene acetals at room temperature without needing extra solvents.

## Contribution

The paper introduces a simplified and improved synthesis protocol for aroyl-S,N-ketene acetals under milder conditions.

## Key findings

- The synthesis achieves 20–99% yields at room temperature in short reaction times.
- The method avoids the need for solubilizing alcohol cosolvents and elevated temperatures.

## Abstract

Aroyl-S,N-ketene acetals are obtained by condensation of aroyl chlorides and 2-methyl-N-benzylbenzothiazolium salts in 1,4-dioxane at room temperature in short reaction time in 20–99% yield. This protocol represents a considerable improvement over the standard synthesis in 1,4-dioxane/ethanol mixtures at elevated temperatures.