# Front Cover

## TL;DR

This study shows that Qishiwei Zhenzhu pills help protect the brain from injury by reducing cell death through a specific biological pathway.

## Contribution

The study identifies a novel mechanism by which Qishiwei Zhenzhu pills protect against cerebral ischemia via the P53/cytochrome C/ apoptotic protease activating factor 1 pathway.

## Key findings

- Qishiwei Zhenzhu pills reduce mitochondrial apoptosis in cerebral ischemia.
- The protective effect is mediated through the P53/cytochrome C/apoptotic protease activating factor 1 pathway.
- This pathway is crucial in preventing cell death after brain injury.

## Abstract

The cover image is based on the article Qishiwei Zhenzhu pills protect against cerebral ischemia via the P53/cytochrome C/apoptotic protease activating factor 1‐mediated mitochondrial apoptosis pathway by Yinglian Song et al., https://doi.org/10.1111/cns.70476.