Infected pericardial effusion caused by Prevotella intermedia: a rare diagnosis
Wan Xu, Dan Han, Tianyang Chen, Qian Wang
TL;DR
This paper reports a rare case of pericardial effusion caused by Prevotella intermedia in China, highlighting the role of mNGS in its detection.
Contribution
The first documented case of Prevotella intermedia in pericardial effusion in China using mNGS.
Findings
Prevotella intermedia was detected in pericardial effusion using mNGS.
Routine laboratory assays failed to detect the bacterium.
mNGS provides early guidance for clinical management of such infections.
Abstract
Prevotella intermedia is a Gram-negative bacterium that thrives in anaerobic environments. It presents challenges in detection through routine laboratory assays, and hitherto, there has been no documented instance of detecting this bacterium in pericardial effusion in China. Metagenomic Next-Generation Sequencing (mNGS) can boost the detection rate of this pathogen and furnish early guidance for clinical management.
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Taxonomy
TopicsBacterial Identification and Susceptibility Testing · Infective Endocarditis Diagnosis and Management · Diphtheria, Corynebacterium, and Tetanus