# Recurrent Pelvic Inflammatory Disease After Serial Intrauterine Inseminations

**Authors:** Lubos Karasek, Pavla Svobodova, Imrich Kiss, Jan Smetana

PMC · DOI: 10.1155/crog/1426202 · 2025-06-22

## TL;DR

This paper discusses a rare but serious complication of intrauterine insemination, where a patient experienced repeated pelvic inflammatory disease.

## Contribution

The paper presents a unique case of recurrent pelvic inflammatory disease following multiple intrauterine inseminations.

## Key findings

- Recurrent pelvic inflammatory disease can occur after serial intrauterine inseminations.
- Prompt diagnosis and individualized therapy are crucial to prevent fertility damage.
- The risk of pelvic inflammatory disease from IUI is low but can have severe consequences.

## Abstract

Introduction: Intrauterine insemination is a basic method of assisted reproduction. It enables direct deposition of sperm inside the uterine cavity. The complications are rare. Multiple pregnancy or ovarian hyperstimulation can occur when concomitant ovulation induction is performed. The risk of pelvic inflammatory disease due to the artificial cervical barrier breach is very low, but the possible consequences are serious.

Case presentation: We present a case of recurrent pelvic inflammatory disease following consecutive intrauterine inseminations. Pelvic inflammatory disease pathophysiology and treatment approaches are discussed.

Conclusion: Inflammatory complications of the IUI are rare, but the possible impact on fertility can be devastating. Prevention of the PID together with prompt diagnosis and individualized therapy should be assured to preserve fertility.

## Linked entities

- **Diseases:** pelvic inflammatory disease (MONDO:0000922)

## Full-text entities

- **Diseases:** Pelvic Inflammatory Disease (MESH:D000292), Inflammatory (MESH:D007249)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12206568/full.md

---
Source: https://tomesphere.com/paper/PMC12206568