Risperidone-Induced Urinary Retention: A Case Report Highlighting Urological Complications in Long-Term Use of Antipsychotic Medication

TL;DR

A 54-year-old man developed urinary retention linked to long-term risperidone use, highlighting the need for awareness of antipsychotic side effects in urological issues.

Contribution

This case report adds to the limited literature on risperidone-induced urinary retention and emphasizes clinical awareness of antipsychotic side effects.

Findings

A 54-year-old male experienced multiple episodes of urinary retention linked to risperidone use.

The patient's complications included hematuria, hydronephrosis, and hospital admissions.

The case underscores the importance of considering medication side effects in recurrent urological issues.

Abstract

Urinary retention is a urological emergency that can lead to serious complications if left untreated. Although rare, risperidone has been associated with urinary retention through anticholinergic effects and modulation of dopaminergic and serotonergic pathways, which can inhibit detrusor muscle contractility and increase urethral sphincter activity. This report presents the case of a 54-year-old male patient who experienced multiple episodes of urinary retention that resulted in gross hematuria, hydronephrosis, and hospital admissions; this was considered to be caused by risperidone, which he was taking for bipolar disorder. This case highlights the importance of considering medication side effects in patients with recurrent urological issues, particularly those with multiple comorbidities. By contributing to the limited literature on risperidone-induced urinary retention, this report aims to enhance clinical awareness and guide decision-making in similar presentations.

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