Bone wax spacers increase induced membrane thickness and promote osteogenesis more than polymethylmethacrylate spacers in the masquelet technique
Takushi Nakatani, Hajime Mishima, Sho Totsuka, Ryunosuke Watanabe, Norihito Arai, Yohei Tomaru, Hisashi Sugaya, Tomofumi Nishino, Masashi Yamazaki
TL;DR
This study shows that bone wax spacers create thicker membranes and better bone growth than PMMA spacers in a bone repair technique.
Contribution
The study provides new histological evidence that bone wax spacers outperform PMMA in the Masquelet technique.
Findings
Bone wax spacers created significantly thicker induced membranes than PMMA spacers.
Bone wax spacers resulted in a higher vascular area ratio compared to PMMA spacers.
Bone wax spacers promoted greater bone formation than PMMA spacers.
Abstract
The Masquelet technique is a recent novel treatment for severe bone defects. Polymethylmethacrylate (PMMA) has been used as a spacer for bone defects, but the optimal spacer is still unknown. Therefore, this study aimed to histologically evaluate the membranes induced by bone wax and PMMA spacers and compare them with respect to bone formation. In this study, bone defects were created in the femurs of Sprague–Dawley rats, and bone wax and PMMA spacers were implanted into the defects to histologically evaluate the induced membrane and bone formation after bone grafting. As a result, the induced membrane formed by bone wax spacers was significantly thicker than that formed by PMMA spacers, and the vascular area ratio was significantly higher. In addition, bone wax spacers promoted bone formation more than PMMA spacers. Bone wax spacers promoted induced membrane formation and bone…
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Taxonomy
TopicsBone fractures and treatments · Orthopaedic implants and arthroplasty · Orthopedic Infections and Treatments