A 5-year retrospective outlook of cardiovascular risk(s), outcome and survival peculiarities among patients in medical confinement; a tropical perspective

TL;DR

This study examines cardiovascular risks and survival patterns among hospitalized patients in a Nigerian hospital over five years, highlighting the impact of non-infectious diseases.

Contribution

The study provides a tropical perspective on cardiovascular risk and survival in medically confined patients.

Findings

Non-infectious diseases were the main cause of hospitalization (82.9%).

Neurological conditions had the highest case fatality rate (27.2%).

Age, occupation, and duration of confinement significantly influenced clinical outcomes.

Abstract

The study was designed to evaluate the distribution of cardiovascular risk(s), outcome modifiers and survival peculiarities among medically confined patients.

Evaluated admission and discharge summaries of medically confined patients retroactively over 5 years.

Medical wards, UniOsun Teaching Hospital Osogbo, Osun State, Nigeria.

Two thousand three hundred and forty (2340) male and female patients aged between 16 and 108 years.

Admission pattern, cardiovascular risk distribution, outcome and survival peculiarities.

The mean age of the respondents was 53.2 (18.3) years with male preponderance (52.0%). Non-infectious diseases predominated as the principal causes of medical confinements (82.9%). Cerebrovascular accident (13.5%), acute decompensation of chronic kidney disease (11.6%) and type 2 diabetes mellitus (6.0%) were the prominent causes of morbidity. The median duration of confinement was 6.0 days. The overall crude mortality rate was 14.3%, with the highest case fatality rate (27.2%) among those with neurological morbidities. Clinical outcome was statistically influenced by age (p= 0.004), occupation (p=0.02), duration of confinement (p=0.002) and morbidity stratification into infectious/non-infectious aetiologies (p=0.040) on regression analysis. The number of medical sub-specialties involved (p < 0.001), specialty affected (p<0.001), and yearly pattern of hospitalisation (p< 0.001) had a statistical influence on Kaplan Meier's survival plots.

Hospital confinements underlined by infection/non-infection-related medical causes exhibit variable outcomes. The loop-sided frequencies of its causes remain worrisome because of the unending challenges plaguing effective healthcare delivery in the tropics.

None declared

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