# Comparison of custom-designed oral stents in radiotherapy for head and neck malignancies

**Authors:** Shihang Li, Guobao Pang, Rong Li, Qinying Shi, Yannan Xu, Ying Lu, Jianbo Song

PMC · DOI: 10.3389/fbioe.2025.1544105 · Frontiers in Bioengineering and Biotechnology · 2025-06-13

## TL;DR

This study compares 3D-printed oral stents with hand-made ones for head and neck cancer radiotherapy, finding that 3D-printed stents are faster to make and more satisfying for patients.

## Contribution

The novelty lies in demonstrating the effectiveness and efficiency of 3D-printed oral stents in head and neck radiotherapy.

## Key findings

- 3D-printed stents (3D-OS) had similar HI and CI to hand-made stents but were fabricated faster.
- 3D-OS showed higher resolution and patient satisfaction compared to hand-made stents.
- Both stent types resulted in similar dose distributions to organs at risk.

## Abstract

To compare the 3D-printed oral stents (3D-OS) and personalised hand-made stents in dentistry (DentStent) for head and neck malignancies.

Twelve patients with head and neck malignant tumours in the Cancer Centre of Shanxi Bethune Hospital from 1 August 2023 to 31 September 2024 were admitted to the study. After obtaining informed consent from the patients, 3D-OS and DentStent were designed for each patient, respectively, and the patients wore them to produce two groups of radiotherapy plans. The aim was to compare the homogeneity index (HI) and conformity index (CI) of the target areas, as well as the dose differences to the organs at risk (OAR) between the two plans. Additionally, the satisfaction of the patients with the stents after use was assessed.

The difference in HI, CI and OAR dose to the target area between the two groups was slight, but 3D-OS took less time (∼4 h) to fabricate and resulted in higher resolution and patient satisfaction.

The proposed 3D-OS could obtain good HI and CI in radiotherapy for head and neck malignancies, and is a new method for rapid and satisfactory personalised oral stent.

## Full-text entities

- **Diseases:** Cancer (MESH:D009369), head and neck malignancies (MESH:D006258)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12202590/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC12202590/full.md

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Source: https://tomesphere.com/paper/PMC12202590