# Peritoneal metastasis of high-grade glioma via Ventriculoperitoneal shunt

**Authors:** Hawro T Hamza, Huda S Sulaiman, Muazzaz G Jaafar, Savan S Shengola, Bahkan J Saeed, Sami S Omar, Fahmi M Fatah, Kakil I Rasul, Saadi A Surchi, Fayrooz A Kakasur, Mohammed N Gheni, Chinar A Mustafa

PMC · DOI: 10.1093/omcr/omaf080 · Oxford Medical Case Reports · 2025-06-27

## TL;DR

A rare case of brain tumor spreading to the abdomen through a medical device used to treat brain fluid buildup is reported, highlighting the need for awareness and better strategies.

## Contribution

This paper reports a rare case of peritoneal metastasis of high-grade glioma via a VP shunt, emphasizing its clinical significance.

## Key findings

- An 18-year-old female with high-grade glioma developed peritoneal metastasis one year after VP shunt placement.
- VP shunt-related metastasis is a rare but important clinical complication requiring awareness for diagnosis and treatment.

## Abstract

High-grade gliomas (HGGs) are aggressive primary brain tumors with a poor prognosis. Although extracranial metastasis is uncommon, peritoneal dissemination via ventriculoperitoneal (VP) shunts is extremely rare. Here, we describe the case of an 18-year-old female with HGG who developed peritoneal metastasis one year after VP shunt placement. Although VP shunting in the presence of an intracranial high-grade tumor is generally not contraindicated, shunt-related metastasis should be recognized as a potential risk and an important, albeit rare, clinical presentation. This case highlights the diagnostic challenges and therapeutic limitations of this rare complication. Understanding this phenomenon is crucial for developing effective monitoring and treatment strategies.

## Linked entities

- **Diseases:** high-grade glioma (MONDO:0100342)

## Full-text entities

- **Diseases:** metastasis (MESH:D009362), brain tumors (MESH:D001932), glioma (MESH:D005910), HGGs (MESH:D008228), Peritoneal (MESH:D010538), tumor (MESH:D009369)

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12202301/full.md

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Source: https://tomesphere.com/paper/PMC12202301