# Euglycemic diabetic ketoacidosis of unknown Etiology in a type 2 diabetic patient

**Authors:** Katrina J Villegas, Laura Guerrero, Hala Moussa, Islam Rajab, Abraam Rezkalla, Dhruv Patel, Mohammed A Qarqash

PMC · DOI: 10.1093/omcr/omaf057 · Oxford Medical Case Reports · 2025-06-27

## TL;DR

A rare case of euglycemic diabetic ketoacidosis in a type 2 diabetic patient with kidney disease highlights the importance of early detection for better outcomes.

## Contribution

This case report adds to the limited literature on euglycemic DKA in type 2 diabetes, emphasizing its recognition in complex patients.

## Key findings

- A 45-year-old female with type 2 diabetes and chronic kidney disease developed euglycemic DKA.
- Treatment involved fluids, insulin with dextrose, and intensive monitoring.
- The case highlights the need for early recognition of euglycemic DKA to improve patient outcomes.

## Abstract

Euglycemic diabetic ketoacidosis is a rare form of DKA characterized by severe ketosis and metabolic acidosis without marked hyperglycemia. We report a 45-year-old female with insulin-dependent diabetes and chronic kidney disease, initially presenting with acute heart failure, who later developed euglycemic DKA. Despite near-normal glucose levels, high anion gap metabolic acidosis with significant ketones highlighted this crisis. Treatment included fluids, insulin with dextrose, and intensive monitoring. This case underscores the need for early recognition of euglycemic DKA, especially in complex patients, to improve outcomes.

## Linked entities

- **Diseases:** diabetic ketoacidosis (MONDO:0012819), chronic kidney disease (MONDO:0005300)

## Full-text entities

- **Diseases:** metabolic acidosis (MESH:D000138), DKA (MESH:D016883), hyperglycemia (MESH:D006943), insulin-dependent diabetes (MESH:D003922), chronic kidney disease (MESH:D051436), acute (MESH:D000208), ketosis (MESH:D007662), heart failure (MESH:D006333), type 2 diabetic (MESH:D003924)
- **Chemicals:** ketones (MESH:D007659), dextrose (MESH:D005947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12202299/full.md

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Source: https://tomesphere.com/paper/PMC12202299