Being in the right place at the right time
Sonia Ancoli-Israel

TL;DR
The paper recounts a sleep researcher's journey and contributions to understanding sleep disorders in aging, Alzheimer’s, Parkinson’s, and cancer patients.
Contribution
The author pioneered studies on sleep and circadian rhythms in aging and neurodegenerative diseases, including early work on sleep apnea and light therapy in nursing homes.
Findings
Sleep apnea and periodic limb movements are common in the elderly.
Light therapy improved sleep in nursing home residents.
Sleep and circadian rhythms were studied in breast cancer patients before chemotherapy.
Abstract
This paper is a review of my life as a sleep researcher and clinician. I chanced into sleep by being at the right place at the right time. Over the last 45 years, I became an expert on sleep and circadian rhythms in aging, in Alzheimer’s disease and Parkinson’s disease and in cancer. We were one of the first to show how common sleep apnea and periodic limb movements in sleep are in the elderly. We “moved” into the nursing home and showed how disrupted sleep is in these patients. We used light therapy to improve sleep in the nursing home. We studied the effect of CPAP on sleep and cognition in both Alzheimer’s disease and Parkinson’s disease. And we were some of the first to study sleep and circadian rhythms in women with breast cancer, starting the evaluations before they started their chemotherapy. These studies were both observational and treatment studies. I am very proud of the work…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 10
Figure 11
Figure 12
Figure 13
Figure 14
Figure 15
Figure 16
Figure 17
Figure 18
Figure 19
Figure 2
Figure 20
Figure 21
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsDementia and Cognitive Impairment Research · Sleep and related disorders
