# Retraction: USP22 protects against myocardial ischemia–reperfusion injury via the SIRT1-p53/SLC7A11–dependent inhibition of ferroptosis–induced cardiomyocyte death

**Authors:** Frontiers Editorial Office

PMC · DOI: 10.3389/fphys.2025.1641580 · 2025-06-12

## Full-text entities

- **Genes:** USP22 (ubiquitin specific peptidase 22) [NCBI Gene 23326] {aka USP3L}, SLC7A11 (solute carrier family 7 member 11) [NCBI Gene 23657] {aka CCBR1, xCT}, SIRT1 (sirtuin 1) [NCBI Gene 23411] {aka SIR2, SIR2L1, SIR2alpha}, TP53 (tumor protein p53) [NCBI Gene 7157] {aka BCC7, BMFS5, LFS1, P53, TRP53}
- **Diseases:** reperfusion injury (MESH:D015427), cardiomyocyte death (MESH:D003643), myocardial ischemia (MESH:D017202)

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Source: https://tomesphere.com/paper/PMC12198966