# A de novo meningioma with rapid growth: A possible malignancy imposter?

**Authors:** Zhenjiang Pan, Jing Bao, Shepeng Wei

PMC · DOI: 10.1515/biol-2025-1118 · 2025-06-12

## TL;DR

An 88-year-old patient successfully underwent surgery for a meningioma, showing that age should not prevent treatment.

## Contribution

This case challenges the assumption that advanced age limits surgical treatment for meningiomas.

## Key findings

- An 84-year-old patient with a meningioma underwent successful surgery at age 88.
- The tumor was confirmed as a WHO grade 1 fibrous meningioma, indicating a benign condition.
- The case supports proactive surgical management in elderly patients with thorough preoperative evaluation.

## Abstract

Meningiomas, accounting for approximately 33% of primary central nervous system tumors, are the most prevalent type in this category. Advanced age is frequently viewed as a barrier to surgical intervention, yet recent cases have challenged this perception by demonstrating successful outcomes in elderly patients. This case report aims to illustrate the feasibility and benefits of surgical treatment in older individuals. An 84-year-old patient presented with a newly diagnosed meningioma and underwent surgical tumor removal at age 88. Following a comprehensive preoperative evaluation that excluded significant comorbidities, the procedure utilized advanced surgical techniques and optimized postoperative care to ensure safety and recovery. Pathology revealed a World Health Organization grade 1 fibrous meningioma, confirming its benign nature. The patient tolerated the surgery well and recovered successfully, marking her as the oldest reported individual to undergo such treatment. This case demonstrates that advanced age does not inherently limit tumor growth or preclude surgical intervention. Through meticulous patient assessment and personalized treatment strategies, elderly patients can achieve positive outcomes. It highlights the value of a tailored approach, prioritizing overall health and specific medical needs, and supports proactive surgical management to enhance quality of life and clinical results. This challenges traditional assumptions about age-related restrictions on surgical feasibility.

## Linked entities

- **Diseases:** meningioma (MONDO:0003057)

## Full-text entities

- **Diseases:** malignancy imposter (MESH:C000711547), Meningiomas (MESH:D008579), nervous system tumors (MESH:D009423), tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12198944/full.md

---
Source: https://tomesphere.com/paper/PMC12198944