# Stellate Ganglion Block to Increase Defibrillation Effectiveness in Acute Fulminant Myocarditis-Induced Refractory Ventricular Fibrillation

**Authors:** Arianna Morena, Carol Gravinese, Simone Frea, Filippo Angelini, Andrea Saglietto, Marinella Zanierato, Monica Andriani, Paolo Scacciatella, Gaetano Maria De Ferrari, Veronica Dusi

PMC · DOI: 10.1016/j.jaccas.2025.103752 · 2025-06-18

## TL;DR

A medical case shows that a nerve block can help control dangerous heart rhythms in a severe heart condition.

## Contribution

This is the first reported use of stellate ganglion block in acute fulminant myocarditis-induced refractory ventricular fibrillation.

## Key findings

- Percutaneous left stellate ganglion block restored stable sinus rhythm in refractory ventricular fibrillation.
- The block improved defibrillation effectiveness in a case unresponsive to standard treatments.
- Acute neuromodulation may enhance defibrillation success in severe heart conditions.

## Abstract

Percutaneous left stellate ganglion block (PLSGB) is used to prevent ventricular arrhythmia recurrences in various settings. Clinical data on its impact on ventricular fibrillation (VF) defibrillation threshold are scant and limited to acute coronary syndromes.

We present a case of refractory VF in acute fulminant myocarditis. Despite multiple drugs and hemodynamic mechanical support, the VF was unresponsive to several DC shock attempts, including double sequential and vector change defibrillation. PLSGB allowed stable sinus rhythm restoration.

PLSGB was performed to enhance the success of DC shock, highlighting the importance of acute neuromodulation strategies not only to prevent ventricular arrhythmia recurrences but also to improve defibrillation effectiveness. Our case is the first reported PLSGB usage in acute fulminant myocarditis-induced refractory VF.

## Linked entities

- **Diseases:** ventricular fibrillation (MONDO:0000190)

## Full-text entities

- **Diseases:** Myocarditis (MESH:D009205), PLSGB (MESH:D045888), VF (MESH:D014693), acute coronary syndromes (MESH:D054058), ventricular arrhythmia (MESH:D001145)
- **Chemicals:** Stellate Ganglion Block (-)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12198641/full.md

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Source: https://tomesphere.com/paper/PMC12198641