# Prodrug–carboxypeptidase G2 therapy: certain concerns on carboxypeptidase G2

**Authors:** Tinghe Yu, Tianran Yu, Xinya Li

PMC · DOI: 10.3389/fphar.2025.1560834 · 2025-06-12

## Full-text entities

- **Genes:** ADA (adenosine deaminase) [NCBI Gene 100] {aka ADA1}
- **Diseases:** lymphoma (MESH:D008223), cancer (MESH:D009369), incoordination (MESH:D001259), ovarian and lung cancers (MESH:D010051), leukemia (MESH:D007938), PK (MESH:C564858), osteosarcoma (MESH:D012516)
- **Chemicals:** ZD2767P (MESH:C097602), (His) (MESH:D006639), 4-[(2-chloroethyl) (2-mesyloxylethyl)amino]benzoyl-L-glutamic acid (-), CMDA (MESH:C092574), Met (MESH:D008715), MTX (MESH:D008727)
- **Species:** Pseudomonas sp. (species) [taxon 306], Homo sapiens (human, species) [taxon 9606]
- **Mutations:** G122S, I99T, T328A

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12198612/full.md

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Source: https://tomesphere.com/paper/PMC12198612