Adult rhabdomyoma: Rare differential diagnosis in frozen section examination
Marvin Seidel, Martin Bredt, Hans Kreipe, Nora Schaumann

TL;DR
This case study discusses the rare diagnosis of adult rhabdomyoma in a laryngeal tumor during a frozen section examination.
Contribution
The paper highlights the diagnostic challenges of adult rhabdomyoma in frozen sections and its differential diagnosis.
Findings
The frozen section initially suggested a benign lesion, but final diagnosis was adult rhabdomyoma.
Immunohistochemistry and morphology after paraffin embedding confirmed the diagnosis.
The case emphasizes the difficulty in diagnosing large-cell lesions in the larynx during frozen sections.
Abstract
Wir berichten über einen 73-jährigen Patienten mit vorbekanntem malignem Melanom und neu aufgefallenem Tumor im Larynx. In der Schnellschnittuntersuchung fand sich kein Anhalt für Malignität. Differentialdiagnostisch wurde zunächst an einen Granularzelltumor gedacht. Die Immunhistochemie und die Morphologie nach Umbettung in Paraffin erbrachten dann die abschließende Diagnose eines adulten Rhabdomyoms. Diese Kasuistik beleuchtet die histomorphologische und immunhistochemische Differentialdiagnose großzelliger Läsionen im Larynx, mit besonderem Fokus auf die Herausforderung im Schnellschnitt.
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Taxonomy
TopicsTuberous Sclerosis Complex Research · Tumors and Oncological Cases · Histiocytic Disorders and Treatments
