Depressive and Insomnia Symptoms Among Older Adults With Different Chronic Pain Trajectories: A Network Analysis Based on Observation Over an Eight-Year Period

TL;DR

This study explores how chronic pain, depression, and insomnia are connected in older adults over eight years, identifying key symptoms for intervention.

Contribution

The paper introduces a network analysis approach to understand the interplay of chronic pain, depression, and insomnia in older adults.

Findings

Three chronic pain trajectories were identified: severe, moderate, and non/mild pain.

Key central symptoms included 'Lack of happiness,' 'Feeling depressed,' and 'Feeling sad,' while 'Feeling tired in the morning' was a key bridge symptom.

Depression and insomnia showed similar network structures across different pain groups.

Abstract

Background: Depressive and insomnia symptoms are common among older adults with chronic pain. We aimed to examine different chronic pain trajectories of older adults over an 8-year observation period and explore the network structures of depression and insomnia in each chronic pain group.

Methods: The trajectories of pain in the USA-based Health and Retirement Study (HRS) data from 2010 to 2018 were examined using latent class growth analyses (LCGA) method. Depressive and insomnia symptoms were measured with the eight-item version of the Center for Epidemiological Studies Depression (CESD-8) Scale and the four-item Jenkins Sleep Scale (JSS-4), respectively. Network models were constructed using the Ising model. Central symptoms and bridge symptoms were identified via expectedInfluence (EI) and bridge EI, respectively.

Results: A total of 11,132 older adults were included in the trajectory analysis, with three chronic pain trajectories identified, including “severe pain trajectory,” “moderate pain trajectory,” and “non or mild pain trajectory”. From these trajectories, “Lack of happiness” (CESD4), “Feeling depressed” (CESD1), and “Feeling sad” (CESD7) emerged as the most central symptoms, while “Feeling tired in the morning” (JSS4) was identified as the key bridge symptom. However, the findings may not be generalizable to other parts of the world outside the USA.

Conclusion: Older adults with different chronic pain trajectories exhibited similar depression and insomnia network structure. Implementing timely interventions that target central and bridge symptoms might mitigate the co-occurrence of depression and insomnia in this population.

Figures