# Effect of Grape Pomace Inclusion in the Diet of Ewes Naturally Infected with Gastrointestinal Nematodes During Lactation

**Authors:** Mateus Oliveira Mena, Gustavo Gabriel de Oliveira Trevise, César Cristiano Bassetto, Willinton Hernan Pinchao Pinchao, Helder Louvandini, Ricardo Velludo Gomes de Soutello, Ana Cláudia Alexandre Albuquerque, Alessandro Francisco Talamini do Amarante

PMC · DOI: 10.3390/pathogens14060560 · Pathogens · 2025-06-04

## TL;DR

Adding grape pomace to the diet of lactating ewes may help reduce worm infections and improve productivity, especially in early lactation.

## Contribution

This study demonstrates the potential of grape pomace as a natural supplement to mitigate gastrointestinal nematode effects in sheep.

## Key findings

- Supplemented ewes had significantly lower fecal egg counts on day 14 of lactation.
- Lambs from supplemented ewes had higher weaning weights.
- Supplemented ewes showed improved hematological indicators like packed cell volume and eosinophils.

## Abstract

This study evaluated the feasibility of including grape pomace in the diet of Santa Inês ewes during lactation, aiming to reduce the effects of gastrointestinal nematode (GIN) infections and improve productive performance. Grape pomace, which contains phenolic compounds and tannins, was provided as a dietary supplement, replacing 20% of the concentrate over 28 days of lactation, starting on day 7 after lambing. A total of 18 ewes were used, divided into two groups: supplemented (n = 8) and control (n = 10). The supplemented group showed significant reduction in fecal egg count on day 14 of lactation (p < 0.05) in comparison with the control group. Lambs from the supplemented group had higher weaning weights (p < 0.05). Additionally, the supplemented group showed higher values for packed cell volume and circulating eosinophils, indicating greater resilience to infections. Analysis of anti-L3 IgG against Haemonchus contortus revealed no significant differences between the groups. It is concluded that grape pomace supplementation demonstrated potential to improve hematological and productive parameters in lactating ewes, with more evident effects during early lactation. Although the results suggest a possible complementary role in controlling gastrointestinal nematodes, future studies are needed to confirm and optimize this nutritional strategy.

## Linked entities

- **Species:** Haemonchus contortus (taxon 6289)

## Full-text entities

- **Diseases:** Gastrointestinal Nematodes (MESH:D009349)
- **Chemicals:** tannins (MESH:D013634), Grape Pomace (-)
- **Species:** Haemonchus contortus (barber pole worm, species) [taxon 6289]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12196531/full.md

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12196531/full.md

## References

50 references — full list in the complete paper: https://tomesphere.com/paper/PMC12196531/full.md

---
Source: https://tomesphere.com/paper/PMC12196531