# A Rare Case of Cervical Solitary Fibrous Tumor in a Pediatric Patient: Case Report and Literature Review

**Authors:** Eleonora Becattini, Lorenzo Sgarbanti, Giuseppina Bevacqua, Valentina Grespi, Carlo Conti

PMC · DOI: 10.3390/neurosci6020049 · NeuroSci · 2025-06-01

## TL;DR

This paper reports a rare case of a cervical tumor in a child, highlighting the challenges in diagnosing such tumors and the importance of specific tests for accurate identification.

## Contribution

The novelty lies in presenting a rare pediatric case of cervical solitary fibrous tumor and emphasizing diagnostic challenges and methods.

## Key findings

- Cervical solitary fibrous tumors are rare in pediatric patients.
- Imaging features can resemble meningiomas or schwannomas, leading to potential misdiagnosis.
- CD34 and STAT6 are key immunohistochemical markers for accurate diagnosis.

## Abstract

Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms of fibroblastic origin. In this study, we report a rare case of cervical SFT in a pediatric patient, a rare phenomenon since the incidence is particularly rare in pediatric patients according to the literature. Typical radiological features of the lesion may lead to misdiagnosis. Image study and immunohistochemistry are crucial for its correct diagnosis. Their imaging characteristics often resemble meningiomas or schwannomas, making differential diagnosis challenging. Immunohistochemical markers such as CD34 and STAT6 remain essential for definitive diagnosis.

## Linked entities

- **Proteins:** CD34 (CD34 molecule), STAT6 (signal transducer and activator of transcription 6)

## Full-text entities

- **Genes:** STAT6 (signal transducer and activator of transcription 6) [NCBI Gene 6778] {aka D12S1644, HIES6, IL-4-STAT, STAT6B, STAT6C}, CD34 (CD34 molecule) [NCBI Gene 947]
- **Diseases:** schwannomas (MESH:D009442), SFTs (MESH:D054364), Fibrous Tumor (MESH:D009369), meningiomas (MESH:D008579)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12195715/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12195715/full.md

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Source: https://tomesphere.com/paper/PMC12195715