# Rapid Tests for Viral Upper Airway Respiratory Infections in the Workplace: A Pilot Study on a Professional Football Team

**Authors:** Dimitrios Papagiannis, George D. Vavougios, Kyriakos Yiangou, Evangelos Latzourakis, Foteini Malli, Konstantinos I. Gourgoulianis, Georgios M. Hadjigeorgiou

PMC · DOI: 10.3390/medicina61061072 · 2025-06-11

## TL;DR

A pilot study on a professional football team found that rapid diagnostic tests can help identify respiratory infections, with low positivity rates and no significant difference in infection risk between players and staff.

## Contribution

This study demonstrates the practicality and reliability of multiplex rapid diagnostic tests in identifying respiratory infections in a professional sports setting.

## Key findings

- Only 10 out of 1078 tests were positive for respiratory pathogens, with the highest positivity for Flu-A.
- There was no statistically significant difference in infection risk between football players and staff.
- The use of rapid tests enabled early identification of contagious individuals, improving clinical management.

## Abstract

Background and Objectives: Acute infections among elite athletes are predominantly attributed to upper respiratory tract pathogens. From a practical standpoint, medical personnel responsible for the healthcare of professional football players should be aware of this and develop infection prevention strategies. This pilot study aimed to investigate the prevalence of respiratory infections in football players using multiplex rapid diagnostic tests targeting four respiratory pathogens. Materials and Methods: The mean age of the participants was 32.76 ± 10.96 years. Among the participants, 32 were professional football players, with a mean age of 26.5 years, SD + 5.3, and 18 were members of staff, with a mean age of 44.3 years, SD + 8.6. In the present study, participants were followed up over a period of 6 months (from October 2024 to March 2025). Results: Among the participants and among a total of 1078 tests, 10 tests were found to be positive. We recorded a proportion of 0.46% for Flu-A, 0.27% for Flu-B, 0.18% for SARS-CoV-2, and 0 positive tests for RSV and adenovirus. There were six days of absence for players and staff and the proportion of total absenteeism was calculated as 3.7%. Univariate analysis revealed no statistically significant difference in infection risk between staff and players (odds ratio: 0.3795; 95% confidence interval: 0.07843–1.735). Conclusions: The multiplex rapid diagnostic test platform has a demonstrated ease of use and appears to be a reliable and safe method for distinguishing contagious symptomatic individuals from non-contagious individuals in occupational settings. Early identification of respiratory infections facilitates improved clinical management, thereby enhancing the quality of care for both athletes and supporting staff.

## Linked entities

- **Diseases:** respiratory infections (MONDO:0024355), SARS-CoV-2 (MONDO:0100096)

## Full-text entities

- **Diseases:** respiratory infections (MESH:D012141), respiratory (MESH:D012131), infection (MESH:D007239), Acute infections (MESH:D000208)
- **Species:** Adenoviridae (family) [taxon 10508], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049]

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Source: https://tomesphere.com/paper/PMC12194941