# Comparison of Surgical Outcomes Between Single-Site Laparoscopic Adenomyomectomy and Fundusectomy: Experience from a Single Center

**Authors:** Jae Hyeok Jeong, Yoo Ri Kim, Bo Ram Kim, Ji Won Lee, Seung Yeon Oh, Jeong Hye Yun, Myoung Seok Han, Yong Jung Song, Ki Hyung Kim

PMC · DOI: 10.3390/jcm14124044 · 2025-06-07

## TL;DR

This study compares two minimally invasive surgeries for adenomyosis and finds that fundusectomy is more efficient and less blood-intensive than myomectomy.

## Contribution

The study introduces and evaluates fundusectomy as a novel, uterus-sparing surgical technique for adenomyosis.

## Key findings

- Fundusectomy had shorter operative time (158.19 min) compared to adenomyomectomy (179.11 min).
- Fundusectomy resulted in significantly less blood loss (175.04 mL) than adenomyomectomy (347.97 mL).
- Fundusectomy showed lower postoperative CA125 levels and smaller uterus size over 24 months.

## Abstract

Objective: This study aimed to introduce clinical experience using a new surgical technique, single-port access laparoscopic fundusectomy, a more efficient uterus-sparing surgical method for adenomyosis in patients with no plans for pregnancy. Methods: We performed single-port access laparoscopic myomectomy in 141 patients and single-port access laparoscopic fundusectomy in 124 patients and compared the surgical outcomes. Results: Significant differences in surgical outcomes were observed between the two operating methods. Operative time was 158.19 min (±42.93) in the fundusectomy group and 179.11 min (±56.95) in the adenomyomectomy group (p = 0.001). Estimated blood loss was 175.04 mL (±142.76) in the fundusectomy group and 347.97 mL (±409.78) in the adenomyomectomy group (p = 0.000). The fundusectomy group showed smaller uterus size and volume, and lower postoperative CA125 levels than the adenomyomectomy group for 24 months (p = 0.000). Conclusions: This study suggests that single-port access laparoscopic fundusectomy is more effective in terms of operative time, estimated blood loss, and postoperative CA125 decrease than single-port access laparoscopic adenomyomectomy.

## Linked entities

- **Diseases:** adenomyosis (MONDO:0010888)

## Full-text entities

- **Genes:** MUC16 (mucin 16, cell surface associated) [NCBI Gene 94025] {aka CA125}
- **Diseases:** adenomyosis (MESH:D062788), blood loss (MESH:D016063)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12194309/full.md

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Source: https://tomesphere.com/paper/PMC12194309