# Idiopathic Ventricular Arrhythmias Originating from the Left Ventricular Summit: A Diagnostic and Therapeutic Challenge

**Authors:** Raffaele Falco, Chiara Tognola, Lorenzo Gigli, Matteo Baroni, Antonio Frontera, Marisa Varrenti, Alberto Preda, Marco Carbonaro, Roberto Menè, Leandro Fabrizio Milillo, Andrea Sultana, Sara Vargiu, Giulia Colombo, Federica Giordano, Cristina Giannattasio, Patrizio Mazzone, Fabrizio Guarracini

PMC · DOI: 10.3390/jcm14124261 · 2025-06-16

## TL;DR

This paper discusses the challenges in diagnosing and treating heart rhythm issues originating from a specific area of the left ventricle.

## Contribution

The paper highlights the unique electrocardiographic features and management strategies for arrhythmias from the left ventricular summit.

## Key findings

- PVCs from the left ventricular summit have distinct electrocardiographic features.
- Accurate localization is crucial for effective treatment of these arrhythmias.
- Recent advances in cardiac mapping improve management of this condition.

## Abstract

Premature ventricular contractions (PVCs) originating from the left ventricular summit (LVS) present a diagnostic and therapeutic challenge due to their complex anatomical location. The LVS includes an epicardial area of the left ventricle bordered by major coronary arteries, which has been increasingly recognized as an arrhythmic focus. Idiopathic ventricular arrhythmias from this area may exhibit specific electrocardiographic characteristics, making accurate localization essential for effective management. Methods: This narrative review explores the primary features of this arrhythmia, emphasizing key diagnostic and therapeutic aspects, including both pharmacological and interventional approaches, considering the recent technological advances in cardiac mapping and ablations. Conclusions: PVCs originating from the left ventricular summit (LVS) exhibit characteristic electrocardiographic features. Prompt recognition of this arrhythmia may facilitate appropriate referral for targeted treatment.

## Full-text entities

- **Diseases:** Idiopathic Ventricular Arrhythmias (MESH:D001145), arrhythmic (OMIM:212500), PVCs (MESH:D018879)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12194172/full.md

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Source: https://tomesphere.com/paper/PMC12194172