# A Quantitative Study on Determinants of COVID-19 Vaccine Uptake in a Mandatory Vaccination Workplace Setting in South Africa

**Authors:** Dhirisha Naidoo, Bernard Hope Taderera

PMC · DOI: 10.3390/ijerph22060929 · International Journal of Environmental Research and Public Health · 2025-06-12

## TL;DR

This study explores why workers in South Africa followed a mandatory COVID-19 vaccine policy at work, finding that safety concerns and employer support were key factors.

## Contribution

The study identifies specific determinants of vaccine uptake in a mandatory workplace setting in South Africa.

## Key findings

- 71% of workers vaccinated to prevent spreading COVID-19, and 65% due to the mandatory policy.
- 63% supported the mandatory vaccine policy, citing safer work environments and employer support.
- Only 15% were against the policy, highlighting the overall acceptance in the workplace.

## Abstract

Coronavirus disease 2019 (COVID-19) resulted in significant morbidity and mortality globally. Despite the efficacy of COVID-19 vaccines in reducing morbidity and mortality, uptake in South Africa was sub-optimal due to a number of factors which remain not fully understood, particularly in mandatory vaccination workplace settings. This quantitative, cross-sectional study aimed to understand determinants of COVID-19 vaccination uptake among clinical and non-clinical workers, aged 18 years and older, employed at a large organisation with a mandatory workplace COVID-19 vaccination policy in South Africa. Workers completed a one-off, self-administered, online questionnaire that explored determinants of COVID-19 vaccination, barriers and enablers to accessing vaccines, and perspectives regarding the mandatory workplace vaccine policy. Among the 88 workers enrolled in the study, the frequent reasons for COVID-19 vaccination included preventing the spread of COVID-19 (71%, n = 62), fear of contracting COVID-19 (64%, n = 56), protecting colleagues and patients (63%, n = 55), and the mandatory workplace policy (65%, n = 57). Just under two-thirds of workers (63%, n = 55) were supportive/very supportive of the mandatory COVID-19 vaccine policy. Reasons for support included the fact that vaccination would create a safer work environment, protecting oneself/others from acquiring COVID-19, and receiving support from their employer. Only 15% (n = 13) of workers were not supportive/against the policy. The findings of this study could inform occupational health policy and counselling and support in workplaces in future pandemics.

## Linked entities

- **Diseases:** Coronavirus disease 2019 (MONDO:0100096), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12193624/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12193624/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12193624/full.md

---
Source: https://tomesphere.com/paper/PMC12193624