# Focal Cortical Dysplasia in an Infant With Aplasia Cutis Congenita: A Case Report

## TL;DR

This case report describes an infant with a rare skin condition and a brain abnormality linked to epilepsy.

## Contribution

The novelty lies in highlighting a rare association between aplasia cutis congenita and focal cortical dysplasia in an infant.

## Key findings

- An infant with scalp aplasia cutis congenita had focal cortical dysplasia detected via neuroimaging.
- The cortical dysplasia was located in the right fronto-opercular/insular region.
- The case emphasizes the need for neuroimaging and follow-up in ACC patients with neuroimaging abnormalities.

## Abstract

Aplasia cutis congenita (ACC) is a rare congenital anomaly characterized by a localized absence of skin, most often affecting the scalp. Although often isolated and with a favorable prognosis, it can be associated with other anomalies, including central nervous system malformations. Cortical dysplasia represents a group of disorders caused by abnormal neuronal migration and organization and is a known risk factor for epilepsy. We report the case of a 10-month-old infant with an occipital ACC lesion present since birth. The infant underwent neuroimaging, which revealed a focal area of cortical dysplasia in the right fronto-opercular/insular region. This case highlights the importance of recognizing associated anomalies in patients with ACC and long-term follow-up in the presence of coexisting neuroimaging abnormalities.