# Orthodontics in Pediatric Osteoporosis: A Narrative Literature Review

**Authors:** Anastasia Panagiota Gravia, Heleni Vastardis, Apostolos I. Tsolakis, Artemis Doulgeraki

PMC · DOI: 10.3390/children12060691 · Children · 2025-05-28

## TL;DR

This review explores orthodontic challenges in children with osteoporosis, emphasizing the need for individualized care and multidisciplinary collaboration.

## Contribution

The paper provides a focused narrative review on orthodontic management in pediatric osteoporosis, highlighting clinical challenges and research gaps.

## Key findings

- Children with osteoporosis experience more severe dental and occlusal complications than healthy peers.
- Orthodontic treatment in these patients requires careful planning due to skeletal fragility and systemic comorbidities.
- Multidisciplinary collaboration is essential for managing orthodontic complexity in pediatric osteoporosis.

## Abstract

Osteoporosis is the most common metabolic bone disorder, characterized by reduced bone mass and abnormal bone microarchitecture, resulting in increased bone fragility and a heightened risk of low-energy fractures. Pediatric osteoporosis may be either primary, due to genetic factors, or secondary, arising from chronic diseases and/or their treatment. Oral health and proper occlusion are integral components of overall health, influencing functionality, nutrition, facial aesthetics, and psychosocial development during childhood. Severe malocclusion can adversely affect speech, mastication, appearance, psychological well-being, and social interactions. The aim of this narrative review is to examine the existing literature on orthodontic anomalies and management strategies in pediatric patients with osteoporosis while highlighting clinical challenges, treatment limitations, and areas necessitating further research. A comprehensive literature search was conducted in the PubMed database, focusing on studies involving human subjects aged 3 to 18 years, published in English between 2002 and 2024. The findings indicate that children with osteoporosis present with more severe dental and occlusal complications compared to their healthy peers, often facing increased orthodontic complexity due to skeletal fragility and systemic comorbidities. These challenges necessitate careful, individualized treatment planning and close multidisciplinary collaboration. Although research in this field remains limited due to the rarity of pediatric osteoporosis, recognizing and addressing the specific needs of this population is critical to improving clinical outcomes and guiding future therapeutic approaches.

## Linked entities

- **Diseases:** osteoporosis (MONDO:0005298)

## Full-text entities

- **Diseases:** Osteoporosis (MESH:D010024), fractures (MESH:D050723), malocclusion (MESH:D008310), skeletal fragility (MESH:D005600), bone fragility (MESH:C536063), metabolic bone disorder (MESH:D001851), reduced bone mass (MESH:D001847), orthodontic anomalies (MESH:D000013)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

50 references — full list in the complete paper: https://tomesphere.com/paper/PMC12191042/full.md

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Source: https://tomesphere.com/paper/PMC12191042