# SARS-CoV-2 Coronavirus Disease in Patients with Underlying Congenital Inferior Vena Cava Anomalies

## TL;DR

This paper discusses how a 36-year-old man with a rare heart condition developed severe blood clots after contracting COVID-19.

## Contribution

The paper presents a rare case linking congenital cardiovascular anomalies with severe DVT following COVID-19.

## Key findings

- Patients with congenital cardiovascular anomalies may develop extensive DVT after contracting COVID-19.
- Anticoagulation treatment must be carefully tailored to balance clot prevention and bleeding risks in these patients.

## Abstract

Background: COVID-19-related deep vein thrombosis (DVT) in patients with pre-existing congenital anomalies or genetic diseases of the cardiovascular system has been rarely reported, and a clear definition of best treatment in this setting remains undefined. Methods: We report the rare case of a 36-year-old male patient affected with a congenital cardiovascular anomaly, presenting extensive venous thrombosis following COVID-19-induced coagulopathy. An insight into current treatment strategies in this setting is also reported. Results and Conclusions: COVID-19 disease appears to be a determining factor in the development of extensive DVT in patients with congenital anomalies and genetic disorders. Anticoagulation should be tailored to the individual risk factors, balancing the risk-benefit between prevention of VTE and hemorrhagic complications.