# Clinical Utility of Trabecular Bone Score in Gastroenterology: A Narrative Review

**Authors:** Ivna Olic, Piero Marin Zivkovic, Ivana Tadin Hadjina, Ivan Zaja

PMC · DOI: 10.3390/biomedicines13061331 · Biomedicines · 2025-05-29

## TL;DR

This paper reviews how the trabecular bone score helps assess fracture risk in inflammatory bowel disease patients and its potential in other digestive diseases.

## Contribution

The paper highlights the added value of trabecular bone score in evaluating fracture risk in inflammatory bowel disease patients.

## Key findings

- Trabecular bone score provides additional advantages in assessing fracture risk in glucocorticoid-induced osteoporosis.
- Limited evidence exists on the utility of trabecular bone score in other digestive diseases.
- Combining dual-energy X-ray absorptiometry with trabecular bone score improves fracture risk evaluation in IBD subjects.

## Abstract

Subjects with inflammatory bowel diseases (IBDs) have a higher opportunity for fractures due to the inflammatory potential of the disorder and because of the glucocorticoid therapy that is often inevitable. The fracture risk can be assessed by dual-energy X-ray absorptiometry and can also be combined with assessing the trabecular bone score (TBS). The evaluation of the TBS offers additional advantages in particular conditions, such as glucocorticoid-induced osteoporosis, and thus optimizes the fracture risk evaluation in the IBD subject group. A limited number of studies involving TBS in other digestive diseases is unlikely to provide sufficient evidence regarding the usefulness of TBS in gastroenterology. Our aim is to review the clinical utility of TBS in digestive diseases.

## Linked entities

- **Diseases:** glucocorticoid-induced osteoporosis (MONDO:0000757)

## Full-text entities

- **Diseases:** IBD (MESH:D015212), fracture (MESH:D050723), osteoporosis (MESH:D010024), inflammatory (MESH:D007249), digestive diseases (MESH:D004066)

## Full text

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## Figures

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## References

79 references — full list in the complete paper: https://tomesphere.com/paper/PMC12189327/full.md

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Source: https://tomesphere.com/paper/PMC12189327