# ItemComplex: A Python-based visualization framework for ex-post organization and integration of large language-based datasets

**Authors:** Karina Janson, Karl Gottfried, Olaf Reis, Johannes Kornhuber, Anna Eichler, Michael Deuschle, Tobias Banaschewski, Frauke Nees

PMC · DOI: 10.1192/j.eurpsy.2025.2457 · European Psychiatry · 2025-05-26

## TL;DR

ItemComplex is a Python-based tool that helps organize and visualize large mental health datasets, making it easier to analyze complex data from questionnaires and clinical records.

## Contribution

The novel contribution is a framework for ex-post visualization of large datasets using instrument alignment and content network identification.

## Key findings

- ItemComplex successfully visualized data from four different cohort studies.
- The framework enables reliable navigation and extraction of insights from multi-item instruments.
- It is adjustable for individual datasets and user preferences in research and clinical settings.

## Abstract

Nowadays, both researchers and clinicians alike have to deal with increasingly larger datasets, specifically also in the context of mental health data. Sophisticated tools for dataset visualization of information from various item-based instruments, such as questionnaire data or data from digital applications or clinical documentations, are still lacking, specifically for an integration at multiple levels and for use in both data organization and appropriate construction for its valid use in subsequent analyses.

Here, we introduce ItemComplex, a Python-based framework for ex-post visualization of large datasets. The method exploits the comprehensive recognition of instrument alignments and the identification of new content networks and graphs based on item similarities and shared versus differential conceptual bases within and across data and studies.

The ItemComplex framework was evaluated using four existing large datasets from four different cohort studies and demonstrated successful data visualization across multi-item instruments within and across studies. ItemComplex enables researchers and clinicians to navigate through big datasets reliably, informatively, and quickly. Moreover, it facilitates the extraction of new insights into construct representations and concept identifications within the data.

The ItemComplex app is an efficient tool in the field of big data management and analysis addressing the growing complexity of modern datasets to harness the potential hidden within these extensive collections of information. It is also easily adjustable for individual datasets and user preferences, both in the research and clinical field.

## Full-text entities

- **Diseases:** impairment (MESH:D060825), substance use disorders (MESH:D019966), mental disorders (MESH:D001523), Mental (MESH:D008607), BDI (MESH:D057767), Depression (MESH:D003866), anxiety (MESH:D001007)
- **Chemicals:** CoviDrug (-)
- **Species:** Homo sapiens (human, species) [taxon 9606], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049]

## Full text

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## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12188333/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12188333/full.md

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Source: https://tomesphere.com/paper/PMC12188333