# Pattern and correlates of coronary artery disease among patients referred for coronary angiography at Abuad Multisystem Hospital, Ado-Ekiti, Nigeria: a descriptive cross-sectional study

**Authors:** Oladipo Ayoola Olanipekun, Stephen Olawale Oguntola, Adekunle Kayode Agoke, Adedayo Hakeem Oyebanji, Olamide Nelson Ogidan, Akinola Akinmade, Dhirendrakumar Jayantilal Dave, Anthony Olubunmi Akintomide, Michael Sanusi, Kamar Tayo Adeleke

PMC · DOI: 10.11604/pamj.2025.50.55.45726 · The Pan African Medical Journal · 2025-05-18

## TL;DR

This study describes the prevalence and risk factors for coronary artery disease in Nigeria, finding that diabetes is a major risk and triple vessel disease is common.

## Contribution

The study provides insights into CAD patterns and risk factors in a sub-Saharan African setting with limited angiographic data.

## Key findings

- Diabetes mellitus was an independent risk factor for CAD, increasing risk by over 7-fold.
- Triple vessel disease was the most prevalent CAD pattern among confirmed cases.
- Erythrocyte sedimentation rate was significantly higher in patients with CAD.

## Abstract

coronary artery disease (CAD) is a common cardiovascular disease (CVD) and a notable cause of mortality worldwide. Angiographic diagnosis of CAD is not widely available in sub-Saharan Africa. We assessed the pattern and correlates of CAD among patients referred for coronary angiography in Ado-Ekiti, Nigeria.

patients with clinical suspicion of CAD who were referred for coronary angiography at Afe Babalola University Multi-System Hospital (AMSH) from August 2019 to December 2020 were recruited into the study after a written informed consent was obtained. Serum fasting lipids, electrolytes, urea and creatinine and erythrocyte sedimentation rate (ESR) were assessed. All patients had coronary angiography.

forty-six (46) patients were recruited into the study. The mean age among patients who had CAD was 52.12 years (±10.34). There were 15 (32.6%) females in the study population. CAD was confirmed in 18/46 (39.1%) patients. Triple vessel disease (TVD) was seen in 9/18 (50.0%) of patients who had CAD, hence, the most prevalent CAD disease pattern. ESR was significantly prolonged among patients who had CAD compared to patients who did not have CAD on univariate analysis while diabetes mellitus was an independent risk factor for CAD and conferred a greater than 7-fold risk for CAD (aOR: 7.28, 95% CI 1.15-46.16; p = 0.035).

diabetes mellitus was an independent risk factor for CAD. Triple vessel disease was the most common pattern of CAD in our study. ESR was associated with CAD.

## Linked entities

- **Diseases:** coronary artery disease (MONDO:0005010), diabetes mellitus (MONDO:0005015)

## Full-text entities

- **Diseases:** CVD (MESH:D002318), CAD (MESH:D003324), diabetes mellitus (MESH:D003920), TVD (MESH:C536008)
- **Chemicals:** lipids (MESH:D008055), urea (MESH:D014508), creatinine (MESH:D003404)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12188011/full.md

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Source: https://tomesphere.com/paper/PMC12188011