# Relationship between depression improvement and activities of daily living recovery in patients with fractures

**Authors:** Shunji Araki, Takahiro Ogawa, Yoshikazu Takaesu

PMC · DOI: 10.1002/pcn5.70139 · PCN Reports: Psychiatry and Clinical Neurosciences · 2025-06-24

## TL;DR

Improvement in depression is linked to better recovery of daily living activities in older patients with fractures.

## Contribution

Shows that depression improvement positively affects functional recovery in fracture patients.

## Key findings

- Depression remission is associated with a 0.184 increase in FIM score change.
- Partial depression improvement correlates with a 0.204 increase in FIM score change.
- Antidepressant use is linked to a 0.250 decrease in FIM score change.

## Abstract

This study aimed to investigate the relationship between improvement in depressive symptoms and activities of daily living (ADL) recovery in older patients with fractures in convalescent rehabilitation wards.

A retrospective observational study was conducted with 144 older patients with fractures and depressive symptoms (Geriatric Depression Scale score ≥ 5) on admission, who underwent rehabilitation at a Japanese hospital from 2018 to 2023. ADL recovery was assessed by the Functional Independence Measure (FIM). Patients were classified into three groups based on change in depressive symptoms: remission, partial improvement, and no improvement. Multivariate linear regression analysis was used to evaluate factors associated with change in the FIM score.

Remission (β = 0.184, p = 0.019) and partial improvement in depressive symptoms (β = 0.204, p = 0.009) were positively associated with change in the FIM score. Conversely, antidepressant use (β = −0.250, p = 0.002) was negatively associated with change in the FIM score.

Remission and partial improvement in depressive symptoms positively contributes to ADL recovery in older patients with fractures. Comprehensive interventions addressing both depression and physical function may enhance rehabilitation outcomes. This may improve ADL recovery and long‐term prognosis in older patients with fractures.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** Depression (MESH:D003866), fractures (MESH:D050723)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

67 references — full list in the complete paper: https://tomesphere.com/paper/PMC12187962/full.md

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Source: https://tomesphere.com/paper/PMC12187962