# Knowledge, attitudes, and practices regarding the prevention of intracerebral hemorrhage among hypertensive patients

**Authors:** Qiang Chen, Feng Liu, LingLing Zhang, Yang Jin, Haibin Huang

PMC · DOI: 10.3389/fcvm.2025.1361273 · Frontiers in Cardiovascular Medicine · 2025-06-11

## TL;DR

This study examines how well hypertensive patients understand and manage their risk of brain hemorrhage, finding poor medication adherence and a need for better interventions.

## Contribution

The study identifies key factors influencing proactive behavior in preventing intracerebral hemorrhage among hypertensive patients.

## Key findings

- Hypertensive patients have sufficient knowledge but poor medication adherence.
- Non-smoking and non-drinking are linked to proactive prevention practices.
- Structural equation modeling shows strong direct effects between knowledge, attitude, and practice.

## Abstract

The present study aimed to assess knowledge, attitudes, and practices (KAP) regarding the prevention of intracerebral hemorrhage among hypertensive patients and medication adherence to hypertension.

We conducted a cross-sectional study at the Third People's Hospital of Nantong City between November 4, 2023 and December 4, 2023. Demographic information, KAP and medication adherence scores were collected using an online questionnaire.

Totally 600 valid questionnaires were analyzed. Among these, 443 participants (73.83%) were female, with a mean age of 62.95 ± 15.07 years. The mean scores for knowledge, attitude, practice, and medication adherence were 13.93 ± 2.88, 32.10 ± 3.22, 25.53 ± 3.44, and 3.12 ± 1.85, respectively. Only 3.50% had high medication compliance to hypertension. Multivariate analyses revealed that uncertain about family history of hypertensive intracerebral hemorrhage [OR = 0.378, 95%CI: (0.218–0.656); P = 0.001], no smoking [OR = 4.603, 95%CI: (1.954–10.845); P < 0.001], and no alcohol consumption [OR = 3.522, 95%CI: (1.764–7.033); P < 0.001] were independently associated with proactive practice. Structural equation modeling (SEM) results revealed direct effects between knowledge and attitude (β = 0.999, P < 0.001), knowledge and practice (β = 1.103, P < 0.001), as well as attitude and practice (β = 0.452, P < 0.001).

Hypertensive patients demonstrated sufficient knowledge, positive attitudes, and inactive practices towards preventing intracerebral hemorrhage, coupled with poor medication adherence to hypertension. Developing targeted interventions to address these gaps and promoting a holistic approach is crucial to improving overall patient outcomes in clinical practice.

## Linked entities

- **Diseases:** intracerebral hemorrhage (MONDO:0013792)

## Full-text entities

- **Diseases:** Hypertensive (MESH:D006973), hypertensive intracerebral hemorrhage (MESH:D020299), intracerebral hemorrhage (MESH:D002543)
- **Chemicals:** alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12187756/full.md

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Source: https://tomesphere.com/paper/PMC12187756