# Lymphatic Obstruction and Edema in Neonate due to Left Subclavian Central Venous Catheter

**Authors:** Klaas Koop, Dominique Valérie Clarence de Jel, Joppe Nijman, Barbara Peels, Ellis Peters

PMC · DOI: 10.1155/crpe/2811167 · Case Reports in Pediatrics · 2025-06-17

## TL;DR

Two newborns developed severe, hard-to-treat edema possibly due to a catheter blocking lymphatic flow.

## Contribution

Highlights a rare cause of neonatal edema linked to left subclavian catheter placement.

## Key findings

- Two neonates developed treatment-resistant generalized edema.
- Edema may result from lymphatic obstruction caused by a left subclavian catheter.

## Abstract

There are several causes of generalized edema in sick neonates. We describe two newborns that developed progressive and treatment-resistant generalized edema. We suggest this is due to impaired lymphatic flow from the thoracic duct as a result of a central venous catheter in the left subclavian vein.

## Full-text entities

- **Diseases:** Edema (MESH:D004487), Lymphatic Obstruction (MESH:D008206)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12187447/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12187447/full.md

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Source: https://tomesphere.com/paper/PMC12187447