# The Influence of Deep Margin Elevation and Immediate Dentin Sealing on the Fracture Strength of Premolars Restored With Indirect Inlays: An In Vitro Study

**Authors:** Lulwa E. Al‐Turki, Osamah A. Alsulimani, Khadijah M. Baik, Haytham Othmani, Naif M. Alqarni, Abdullah A. Alqarni, Raghad A. Al‐Dabbagh

PMC · DOI: 10.1002/cre2.70161 · Clinical and Experimental Dental Research · 2025-06-24

## TL;DR

This study finds that deep margin elevation and immediate dentin sealing improve the fracture strength of premolars with inlay restorations.

## Contribution

The study evaluates the combined effect of deep margin elevation and immediate dentin sealing on inlay restorations, showing their impact on fracture strength.

## Key findings

- Deep margin elevation and immediate dentin sealing significantly increased fracture loads in premolars with inlay restorations.
- Groups with either or both techniques had higher fracture strength than the control group without these techniques.
- Catastrophic failure rates varied across groups, with the highest in the control group and lowest when both techniques were used.

## Abstract

To evaluate the effect of deep margin elevation (DME) and immediate dentin sealing (IDS) on the fracture strength of premolars restored with lithium disilicate inlay restorations.

Standard MOD inlays with proximal box preparations extending 3 mm apical to the cementoenamel junction were prepared on forty sound premolars (n = 10) randomly divided into four groups: inlays without DME and without IDS (G1); inlays without DME but with IDS (G2); inlays with DME but without IDS (G3); and inlays with both techniques applied (G4). Composite resin was applied incrementally to elevate the proximal cervical margin coronally to the cementoenamel junction. For immediate dentin sealing, bonding agent was applied immediately after tooth preparation. All teeth were restored with lithium disilicate inlays and, after adhesive resin cementation, specimens were thermomechanically aged for 500 cycles at 5°–55°C and then subjected to load failure testing. Failure loads and locations were recorded and analyzed using one‐ and two‐way ANOVA with Tukey's post‐hoc testing (α = 0.05). Failure modes were analyzed using descriptive statistics.

The mean fracture loads were 565.76 ± 233.22 N, 978.47 ± 394.2 N, 974.31 ± 334.7 N, and 1108.21 ± 292.41 N for G1, G2, G3, and G4, respectively. Deep margin elevation (p = 0.011) and immediate dentin sealing (p = 0.010) were associated with significantly increased fracture loads. Fracture loads were significantly lower for G1 teeth than for G2‐G4 teeth, but there were no significant differences between G2, G3, and G4. G1 teeth showed 50% catastrophic and non‐catastrophic failures, which increased to 60% for G2 and decreased to 20% for G3 teeth. Samples with both seals and elevation (G4) had a 60% catastrophic failure rate.

When applied individually or together, deep margin elevation and immediate dentin sealing significantly increase the fracture strength of premolars restored with indirect lithium disilicate inlays.

In the challenging setting of margin elevation, studies on the effects of immediate dentin sealing have generally been limited to evaluating marginal integrity and bond strength. The findings of this In Vitro study suggest that both deep margin elevation and immediate dentin sealing protocols are likely to improve clinical outcomes of indirect lithium disilicate inlay restorations and may be considered viable options in clinical practice.

## Full-text entities

- **Diseases:** Fracture (MESH:D050723)

## Full text

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## Figures

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## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12186461/full.md

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Source: https://tomesphere.com/paper/PMC12186461