# Gastric schwannoma with atypical manifestations in an adult patient: case report and literature review

**Authors:** Yanet Isabel Carrasco Rojas, Albert Gabriel Turpo Peqqueña, Natalia Camila Zenteno Tejada, Victoria Elena Quispe Pastor, Juan Augusto Martínez San Martín, Evelyn Maria Chambilla Huellcacure

PMC · DOI: 10.3332/ecancer.2025.1910 · 2025-05-27

## TL;DR

A rare case of gastric schwannoma in an adult is reported, highlighting its diagnostic challenges and successful surgical treatment.

## Contribution

This case report adds to the limited literature on gastric schwannomas with atypical clinical manifestations.

## Key findings

- A 61-year-old female presented with gastric fullness and abdominal pain due to a gastric schwannoma.
- Immunohistochemistry confirmed the diagnosis after initial suspicion of a gastrointestinal stromal tumor.
- Surgical resection was effective in treating the gastric schwannoma.

## Abstract

Gastric schwannomas (GS) are rare tumours originating from Schwann cells that affect the gastrointestinal tract, posing a diagnostic challenge due to their nonspecific symptoms. We report the case of a 61-year-old female presented with gastric fullness and occasional episodes of abdominal pain. Computed tomography revealed a solid mass in the lesser curvature of the stomach, initially suspected to be a gastrointestinal stromal tumours. During surgery, an exophytic lesion was identified and confirmed histopathologically and immunohistochemically as a gastric schwannoma. GS should be considered in the differential diagnosis of gastric subepithelial tumours. Its diagnosis relies on immunohistochemistry, and surgical resection ensures effective treatment.

## Linked entities

- **Diseases:** gastrointestinal stromal tumor (MONDO:0011719)

## Full-text entities

- **Diseases:** gastric subepithelial tumours (MESH:D013274), tumours (MESH:D009369), GS (MESH:D009442), gastrointestinal stromal tumours (MESH:D046152), abdominal pain (MESH:D015746)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12185875/full.md

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Source: https://tomesphere.com/paper/PMC12185875