# Rare presentation of multicentric sebaceous carcinoma of the breast in a 33-year-old woman: diagnostic challenges and treatment approach

**Authors:** Izaberen Sampaio Estevam, Mariana Macambira Noronha, Júlia Matos Dubanhevitz, Eric Lima Freitas Mota, Ígor Giordan Duarte Jorge, Conceição Aparecida Dornelas, Diane Isabelle Magno Cavalcante, Georgia Fiuza Alencar Araripe, Márcio Marcondes Vieira

PMC · DOI: 10.3332/ecancer.2025.1908 · 2025-05-15

## TL;DR

This paper presents a rare case of multicentric sebaceous breast carcinoma in a young woman and discusses the challenges in diagnosis and treatment.

## Contribution

The novelty lies in describing a rare, multicentric case of sebaceous breast carcinoma in a 33-year-old patient.

## Key findings

- Sebaceous carcinoma of the breast is extremely rare, with only 30 reported cases.
- The case highlights the diagnostic difficulties and treatment strategies for this uncommon condition.

## Abstract

Background: Sebaceous carcinoma of the breast (SCB) is an unusual neoplasm. To the best of our knowledge, only 30 cases have been reported in the literature. Due to its rarity, there is limited knowledge on how to manage patients with SCB. This article aims to describe a case of multicentric sebaceous breast carcinoma in a 33-year-old woman detailing the diagnostic process, historical findings and the treatment approach.

## Linked entities

- **Diseases:** sebaceous breast carcinoma (MONDO:0003635)

## Full-text entities

- **Diseases:** Sebaceous carcinoma of the breast (MESH:D001943), neoplasm (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12185865/full.md

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Source: https://tomesphere.com/paper/PMC12185865