# Effects of Periodontal Therapy on Blood Lipid Levels in 10 Dogs With Periodontitis and Hyperlipidemia

**Authors:** Yu Sahashi, Miwako Sahashi, Yoshiaki Hikasa

PMC · DOI: 10.1155/crve/9088922 · 2025-06-16

## TL;DR

This study found that treating periodontitis in dogs with high blood lipids significantly lowers their lipid levels.

## Contribution

The novel contribution is demonstrating that periodontal therapy can reduce hyperlipidemia in dogs.

## Key findings

- Periodontal therapy significantly reduced total triglyceride levels in dogs.
- VLDL-triglyceride and total cholesterol levels also decreased after treatment.
- The study suggests periodontitis treatment can ameliorate hyperlipidemia in affected dogs.

## Abstract

This study is aimed at evaluating the effects of periodontal therapy on blood lipid levels in 10 dogs with both periodontitis and hyperlipidemia. A retrospective analysis was conducted on data from 10 client-owned dogs with mild to severe periodontitis and hyperlipidemia. Dental procedures such as periodontal probing and intraoral radiography, followed by scaling, curettage, and polishing, were performed. The teeth were extracted, and the gingival mucosa was sutured in five cases of severe periodontitis. Hematological and general biochemical tests and lipoprotein (i.e., chylomicrons, very low-density lipoprotein (VLDL), low-density lipoprotein, and high-density lipoprotein) analyses were performed before and 4 weeks after periodontal treatments. Consequently, periodontal treatments significantly reduced the total triglyceride, VLDL-triglyceride, and total cholesterol levels. This study suggested that periodontitis treatment effectively ameliorates hyperlipidemia in dogs with both periodontitis and hyperlipidemia.

## Linked entities

- **Diseases:** periodontitis (MONDO:0005076), hyperlipidemia (MONDO:0021187)

## Full-text entities

- **Diseases:** Hyperlipidemia (MESH:D006949), Periodontitis (MESH:D010518)
- **Chemicals:** triglyceride (MESH:D014280), Lipid (MESH:D008055), density (-), cholesterol (MESH:D002784)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615]

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Source: https://tomesphere.com/paper/PMC12185206