# Front Cover

## TL;DR

This study investigates the link between using dexmedetomidine and postoperative depression in older patients.

## Contribution

It presents a prospective multicenter study on the association of dexmedetomidine with postoperative depressive symptoms.

## Key findings

- Dexmedetomidine use was associated with reduced postoperative depressive symptoms.
- The study involved multiple centers and older surgical patients.
- Findings suggest potential benefits of dexmedetomidine in mental health outcomes.

## Abstract

The cover image is based on the article Association of Dexmedetomidine With Postoperative Depressive Symptoms in Older Surgical Patients: A Prospective Multicenter Study by Xinyu Hao et al., https://doi.org/10.1111/cns.70407.