# Inpatient neurosurgical mortality in germany: a comprehensive analysis of 2023 in-hospital data

**Authors:** Marcel A. Kamp, Christine Jungk, Matthias Schneider, Georgia Fehler, Antonio Santacroce, N. Dinc, Florian H. Ebner, Christiane von Sass

PMC · DOI: 10.1007/s10143-025-03664-1 · 2025-06-23

## TL;DR

This paper analyzes inpatient neurosurgical mortality rates in Germany in 2023, revealing variation by diagnosis and procedure.

## Contribution

The study provides a national benchmark for neurosurgical in-hospital mortality in Germany using comprehensive 2023 data.

## Key findings

- Overall in-hospital mortality rate was 3.8% across 222,158 neurosurgical cases in Germany in 2023.
- Mortality rates varied significantly by diagnosis, with intracerebral hemorrhages having the highest rate at 29%.
- Female patients had a lower mortality rate (3.3%) compared to males (4.2%).

## Abstract

Neurosurgical conditions and procedures are associated with varying in-hospital mortality rates, which represent one of several quality indicators. This study aims to determine and report in-hospital mortality rates across German neurosurgical departments in 2023.

A cross-sectional analysis of all neurosurgical cases treated in Germany in 2023 was conducted using nationwide hospital billing data reported under § 21 of the Hospital Remuneration Act. In-hospital mortality was defined as death during hospitalization (discharge status: deceased).

Neurosurgical departments treated 222,158 inpatient cases, with 49% female and 48% aged ≥ 65 years. The overall mortality rate was 3.8% (8,338 cases), with significantly lower rates in females (3.3% vs. 4.2%, p < 0.0001). The most common fatal diagnoses included traumatic subdural hematomas (1,278 cases), subcortical intracerebral hemorrhages (611 cases) and traumatic subarachnoid hemorrhages (504 cases). Mortality rates varied by diagnosis: malignant brain tumors (4%), cerebral metastases (6%), benign meningeal tumors (1.3%), non-traumatic subarachnoid hemorrhages (7%), intracerebral hemorrhages (29%), and traumatic subdural hematomas (12%). Mortality for selected procedures was 3% for primary brain tumor resections, 9% for vascular reconstructions, 1% for spinal fusions, 2% for dynamic stabilizations, and 4% for vertebral body replacements.

This study analyzes and reports neurosurgical in-hospital mortality rates in Germany, providing a national benchmark that may inform clinicians, policymakers, and patients. While the use of administrative billing data imposes inherent limitations — particularly regarding clinical detail and causality — the findings may offer a foundation for future research. Subsequent studies should aim to explore disease- and procedure-specific mortality more granularly and may identify underlying risk factors.

Not applicable.

## Linked entities

- **Diseases:** benign meningeal tumors (MONDO:0021527)

## Full-text entities

- **Diseases:** subarachnoid hemorrhages (MESH:D013345), metastases (MESH:D009362), brain tumor (MESH:D001932), death (MESH:D003643), intracerebral hemorrhages (MESH:D002543), subdural hematomas (MESH:D006408), meningeal tumors (MESH:D008577)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12183133/full.md

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Source: https://tomesphere.com/paper/PMC12183133