# Eyelid Pilomatrixomas: A Case Report and Comprehensive Literature Review

**Authors:** Georgia L Schafer, Krista Thompson, Katie Topping

PMC · DOI: 10.7759/cureus.84639 · 2025-05-22

## TL;DR

This paper presents a rare case of eyelid pilomatrixoma in a 13-year-old girl and reviews existing literature to improve understanding and diagnosis of this condition.

## Contribution

The paper provides a comprehensive literature review and highlights a rare, rapidly progressing eyelid pilomatrixoma case.

## Key findings

- Eyelid pilomatrixomas are rare and can be misdiagnosed due to their similarity to other eyelid conditions.
- Accurate diagnosis requires clinical evaluation, imaging, and histopathology.
- A comprehensive literature review helps clarify management strategies and potential complications.

## Abstract

Pilomatrixomas are rare, benign tumors of the hair follicle that can be found all over the body and, rarely, the eyelid. Despite their benign nature, pilomatrixomas can be misdiagnosed due to their similarity to other eyelid conditions. Diagnosis can be challenging and requires a combination of clinical skills, imaging studies, and histopathology. As a result, a comprehensive understanding of their presentation and management strategies is essential for healthcare providers. Herein, the unusual case of a 13-year-old female patient with a rapidly progressive eyelid pilomatrixoma is presented. A comprehensive review of the current literature regarding eyelid pilomatrixomas was performed. This literature review aims to synthesize existing research and case studies related to pilomatrixomas of the eyelid, focusing on their etiology, differential diagnosis, treatment options, and potential complications.

## Linked entities

- **Diseases:** pilomatrixoma (MONDO:0007564)

## Full-text entities

- **Diseases:** Pilomatrixomas (MESH:D018296), benign tumors (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12182883/full.md

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Source: https://tomesphere.com/paper/PMC12182883